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The Efficiency of CD4 Recruitment to Ligand-engaged TCR Controls the Agonist/Partial Agonist Properties of Peptide–MHC Molecule Ligands

One hypothesis seeking to explain the signaling and biological properties of T cell receptor for antigen (TCR) partial agonists and antagonists is the coreceptor density/kinetic model, which proposes that the pharmacologic behavior of a TCR ligand is largely determined by the relative rates of (a) d...

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Hlavní autoři: Madrenas, Joaquín, Chau, Luan A., Smith, Judy, Bluestone, Jeffrey A., Germain, Ronald N.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196122/
https://ncbi.nlm.nih.gov/pubmed/9016871
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