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Peripheral Expression of Jak3 Is Required to Maintain T Lymphocyte Function

The Jak family tyrosine kinase, Jak3, is involved in signaling through cytokine receptors that utilize the common γ chain (γ(c)), such as those for IL-2, IL-4, IL-7, IL-9, and IL-15. Recent studies of Jak3-deficient mice and humans have demonstrated that Jak3 plays a critical role in B and T lymphoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thomis, Daniel C., Berg, Leslie J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196115/
https://ncbi.nlm.nih.gov/pubmed/9016869
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