Jak3 activation in human lymphocyte precursor cells

Although expression of the Jak3 tyrosine kinase in T lymphocytes has been thought to be restricted to mature, activated cells, mutations of Jak3 can lead to the development of a human severe combined immunodeficiency (SCID) characterized by an absence of peripheral T lymphocytes. We therefore examin...

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Detalhes bibliográficos
Main Authors: SHARFE, N, DADI, H K, O'SHEA, J J, ROIFMAN, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904698/
https://ncbi.nlm.nih.gov/pubmed/9182906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4001304.x
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