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High RAC3 expression levels are required for induction and maintaining of cancer cell stemness

RAC3 is a transcription coactivator, usually overexpressed in several tumors and required to maintain the pluripotency in normal stem cells. In this work we studied the association between RAC3 overexpression on cancer cell stemness and the capacity of this protein to induce cancer stem properties i...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Panelo, Laura C., Machado, Mileni Soares, Rubio, María F., Jaworski, Felipe, Alvarado, Cecilia V., Paz, Leonardo A., Urtreger, Alejandro J., Vazquez, Elba, Costas, Mónica A.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814179/
https://ncbi.nlm.nih.gov/pubmed/29464039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23635
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