Non–T Cell Activation Linker (NTAL): A Transmembrane Adaptor Protein Involved in Immunoreceptor Signaling

A key molecule necessary for activation of T lymphocytes through their antigen-specific T cell receptor (TCR) is the transmembrane adaptor protein LAT (linker for activation of T cells). Upon TCR engagement, LAT becomes rapidly tyrosine phosphorylated and then serves as a scaffold organizing a multi...

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Main Authors: Brdička, Tomáš, Imrich, Martin, Angelisová, Pavla, Brdičková, Naděžda, Horváth, Ondrej, Špička, Jiří, Hilgert, Ivan, Lusková, Petra, Dráber, Petr, Novák, Petr, Engels, Niklas, Wienands, Jürgen, Simeoni, Luca, Österreicher, Jan, Aguado, Enrique, Malissen, Marie, Schraven, Burkhart, Hořejší, Václav
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196071/
https://ncbi.nlm.nih.gov/pubmed/12486104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021405
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