Identification of HLA-A2–restricted CD8(+) Cytotoxic T Cell Responses in Primary Biliary Cirrhosis: T Cell Activation Is Augmented by Immune Complexes Cross-Presented by Dendritic Cells

Primary biliary cirrhosis (PBC) is characterized by an intense biliary inflammatory CD4(+) and CD8(+) T cell response. Very limited information on autoantigen-specific cytotoxic T lymphocyte (CTL) responses is available compared with autoreactive CD4(+) T cell responses. Using peripheral blood monon...

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Main Authors: Kita, Hiroto, Lian, Zhe-Xiong, Van de Water, Judy, He, Xiao-Song, Matsumura, Shuji, Kaplan, Marshall, Luketic, Velimir, Coppel, Ross L., Ansari, Aftab A., Gershwin, M. Eric
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196012/
https://ncbi.nlm.nih.gov/pubmed/11781370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20010956
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