Analysis of Human Telomerase Activity and Function by Two Color Single Molecule Coincidence Fluorescence Spectroscopy

Telomerase is a nonclassical DNA polymerase that uses its integral RNA as a template to synthesize telomeric repeats onto chromosome ends. The molecular mechanism of telomerase is unique and involves a translocation step after the synthesis of each telomeric repeat. To directly measure the enzymatic...

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Bibliographic Details
Main Authors: Ren, Xiaojun, Li, Haitao, Clarke, Richard W., Alves, David A., Ying, Liming, Klenerman, David, Balasubramanian, Shankar
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195889/
https://ncbi.nlm.nih.gov/pubmed/16608333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056613z
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