Therapeutic Activity of an Engineered Synthetic Killer Antiidiotypic Antibody Fragment against Experimental Mucosal and Systemic Candidiasis

Peptides derived from the sequence of a single-chain, recombinant, antiidiotypic antibody (IdAb; KT-scFv) acting as a functional internal image of a microbicidal, wide-spectrum yeast killer toxin (KT) were synthesized and studied for their antimicrobial activity by using the KT-susceptible Candida a...

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Bibliografiska uppgifter
I publikationen:	Infect Immun
Huvudupphov:	Polonelli, Luciano, Magliani, Walter, Conti, Stefania, Bracci, Luisa, Lozzi, Luisa, Neri, Paolo, Adriani, Daniela, De Bernardis, Flavia, Cassone, Antonio
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 2003
Ämnen:	Fungal and Parasitic Infections
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219587/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14573638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.11.6205-6212.2003
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Therapeutic Activity of an Engineered Synthetic Killer Antiidiotypic Antibody Fragment against Experimental Mucosal and Systemic Candidiasis

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