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Plasminogen Activator Inhibitor 1 Functions as a Urokinase Response Modifier at the Level of Cell Signaling and Thereby Promotes Mcf-7 Cell Growth

Plasminogen activator inhibitor 1 (PAI-1) is a major inhibitor of urokinase-type plasminogen activator (uPA). In this study, we explored the role of PAI-1 in cell signaling. In MCF-7 cells, PAI-1 did not directly activate the mitogen-activated protein (MAP) kinases, extracellular signal–regulated ki...

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Detaylı Bibliyografya
Asıl Yazarlar: Webb, Donna J., Thomas, Keena S., Gonias, Steven L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195772/
https://ncbi.nlm.nih.gov/pubmed/11266465
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