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A Balance between Positive and Negative Signals in Cytotoxic Lymphocytes Regulates the Polarization of Lipid Rafts during the Development of Cell-Mediated Killing

Plasma membrane microdomains containing sphingolipids and cholesterol (lipid rafts) are enriched in signaling molecules. The cross-linking of certain types of cell surface receptors initiates the redistribution of these lipid rafts, resulting in the formation of signaling complexes. However, little...

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Main Authors: Lou, Zhenkun, Jevremovic, Dragan, Billadeau, Daniel D., Leibson, Paul J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195747/
https://ncbi.nlm.nih.gov/pubmed/10637278
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