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Pre–T Cell Receptor (Tcr) and Tcr-Controlled Checkpoints in T Cell Differentiation Are Set by Ikaros

T cell differentiation relies on pre–T cell receptor (TCR) and TCR signaling events that take place at successive steps of the pathway. Here, we show that two of these T cell differentiation checkpoints are regulated by Ikaros. In the absence of Ikaros, double negative thymocytes can differentiate t...

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Hlavní autoři: Winandy, Susan, Wu, Li, Wang, Jin-Hong, Georgopoulos, Katia
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195663/
https://ncbi.nlm.nih.gov/pubmed/10523602
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