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The positive and negative regulation of Tn10 transposition by IHF is mediated by structurally asymmetric transposon arms

The Tn10 transpososome has symmetrical components on either side: there are two transposon ends each of which has binding sites for a monomer of transposase and an IHF heterodimer. The DNA bending activity of IHF stimulates assembly of an intermediate with tightly folded transposon ends in which tra...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Sewitz, Sven, Crellin, Paul, Chalmers, Ronald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14530435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg797
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