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The positive and negative regulation of Tn10 transposition by IHF is mediated by structurally asymmetric transposon arms

The Tn10 transpososome has symmetrical components on either side: there are two transposon ends each of which has binding sites for a monomer of transposase and an IHF heterodimer. The DNA bending activity of IHF stimulates assembly of an intermediate with tightly folded transposon ends in which tra...

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Autors principals: Sewitz, Sven, Crellin, Paul, Chalmers, Ronald
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC219475/
https://ncbi.nlm.nih.gov/pubmed/14530435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg797
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