The positive and negative regulation of Tn10 transposition by IHF is mediated by structurally asymmetric transposon arms
The Tn10 transpososome has symmetrical components on either side: there are two transposon ends each of which has binding sites for a monomer of transposase and an IHF heterodimer. The DNA bending activity of IHF stimulates assembly of an intermediate with tightly folded transposon ends in which tra...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14530435/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg797 |
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