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C1q Inhibits Antibody-Dependent Enhancement of Flavivirus Infection In Vitro and In Vivo in an IgG Subclass Specific Manner
Severe dengue virus (DENV) infection occurs in humans with pre-existing antibodies. To explain this, a hypothesis emerged that antibody-dependent enhancement of infection (ADE) increases viral burden and causes more severe disease. In vitro, ADE has been described for multiple viruses, including DEN...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194657/ https://ncbi.nlm.nih.gov/pubmed/18078693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.09.015 |
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