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Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase
The non-homologous end joining pathway uses pre-existing proteins to repair DNA double-strand breaks induced by ionizing radiation. Here we describe manipulation of this pathway in living cells using a newly developed tool. We generated a single chain antibody variable fragment (scFv) that binds to...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC219464/ https://ncbi.nlm.nih.gov/pubmed/14530433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg775 |
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