The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression

Pax5 activity is enhanced in activated B cells and is essential for class switch recombination (CSR). We show that inhibitor of differentiation (Id)2 suppresses CSR by repressing the gene expression of activation-induced cytidine deaminase (AID), which has been shown to be indispensable for CSR. Fur...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gonda, Hiroyuki, Sugai, Manabu, Nambu, Yukiko, Katakai, Tomoya, Agata, Yasutoshi, Mori, Kazuhiro J., Yokota, Yoshifumi, Shimizu, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194241/
https://ncbi.nlm.nih.gov/pubmed/14581609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030802
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares