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Roles of p-ERM and Rho–ROCK signaling in lymphocyte polarity and uropod formation

Front–rear asymmetry in motile cells is crucial for efficient directional movement. The uropod in migrating lymphocytes is a posterior protrusion in which several proteins, including CD44 and ezrin/radixin/moesin (ERM), are concentrated. In EL4.G8 T-lymphoma cells, Thr567 phosphorylation in the COOH...

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Bibliografische gegevens
Hoofdauteurs: Lee, Jong-Hwan, Katakai, Tomoya, Hara, Takahiro, Gonda, Hiroyuki, Sugai, Manabu, Shimizu, Akira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172551/
https://ncbi.nlm.nih.gov/pubmed/15504914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403091
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