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The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration
Complement has been implicated in liver repair after toxic injury. Here, we demonstrate that complement components are essential for liver regeneration, and mediate their effect by interacting with key signaling networks that promote hepatocyte proliferation. C3- or C5-deficient mice exhibited high...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194207/ https://ncbi.nlm.nih.gov/pubmed/12975457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030374 |
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