The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration

Complement has been implicated in liver repair after toxic injury. Here, we demonstrate that complement components are essential for liver regeneration, and mediate their effect by interacting with key signaling networks that promote hepatocyte proliferation. C3- or C5-deficient mice exhibited high...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Strey, Christoph W., Markiewski, Maciej, Mastellos, Dimitrios, Tudoran, Ruxandra, Spruce, Lynn A., Greenbaum, Linda E., Lambris, John D.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194207/
https://ncbi.nlm.nih.gov/pubmed/12975457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030374
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki