Interleukin 2 Signaling Is Required for CD4(+) Regulatory T Cell Function

Mice deficient in interleukin (IL)-2 production or the IL-2 receptor α or β chains develop a lethal autoimmune syndrome. CD4(+) regulatory T cells have been shown to prevent autoimmune diseases, allograft rejection, and to down-regulate antibody responses against foreign antigens. To assess the role...

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Bibliografiska uppgifter
Huvudupphovsmän: Furtado, Gláucia C., de Lafaille, Maria A. Curotto, Kutchukhidze, Nino, Lafaille, Juan J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2002
Ämnen:
Brief Definitive Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194060/
https://ncbi.nlm.nih.gov/pubmed/12235217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020190
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