Lymphangiogenic Gene Therapy With Minimal Blood Vascular Side Effects

Recent work from many laboratories has demonstrated that the vascular endothelial growth factor-C/VEGF-D/VEGFR-3 signaling pathway is crucial for lymphangiogenesis, and that mutations of the Vegfr3 gene are associated with hereditary lymphedema. Furthermore, VEGF-C gene transfer to the skin of mice...

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Autori principali: Saaristo, Anne, Veikkola, Tanja, Tammela, Tuomas, Enholm, Berndt, Karkkainen, Marika J., Pajusola, Katri, Bueler, Hansruedi, Ylä-Herttuala, Seppo, Alitalo, Kari
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194057/
https://ncbi.nlm.nih.gov/pubmed/12235206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020587
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