Cell-Type-Specific Characteristics Modulate the Transduction Efficiency of Adeno-Associated Virus Type 2 and Restrain Infection of Endothelial Cells

Adeno-associated viruses (AAVs) are promising vectors for various gene therapy applications due to their long-lasting transgene expression and wide spectrum of target cells. Recently, however, it has become apparent that there are considerable differences in the efficiencies of transduction of diffe...

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Hlavní autoři: Pajusola, Katri, Gruchala, Marcin, Joch, Hana, Lüscher, Thomas F., Ylä-Herttuala, Seppo, Büeler, Hansruedi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136795/
https://ncbi.nlm.nih.gov/pubmed/12388714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11530-11540.2002
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