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The Proliferative Capacity of Individual Naive CD4(+)T Cells Is Amplified by Prolonged T Cell Antigen Receptor Triggering
Strong antigenic encounter by T cells rapidly induces immunological synapse formation and surface T cell receptor (TCR) downregulation. Although surface TCR expression can remain low for several days, T cells can still sustain antigenic signaling. It has been unclear whether prolonged antigenic sign...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194051/ https://ncbi.nlm.nih.gov/pubmed/12235212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020158 |
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