Delayed Apoptotic Cell Clearance and Lupus-like Autoimmunity in Mice Lacking the c-mer Membrane Tyrosine Kinase

Mice lacking the membrane tyrosine kinase c-mer have been shown to have altered macro-phage cytokine production and defective phagocytosis of apoptotic cells despite normal phagocytosis of other particles. We show here that c-mer–deficient mice have impaired clearance of infused apoptotic cells and...

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Détails bibliographiques
Auteurs principaux: Cohen, Philip L., Caricchio, Roberto, Abraham, Valsamma, Camenisch, Todd D., Jennette, J. Charles, Roubey, Robert A.S., Earp, H. Shelton, Matsushima, Glenn, Reap, Elizabeth A.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2002
Sujets:
Brief Definitive Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194017/
https://ncbi.nlm.nih.gov/pubmed/12093878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20012094
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