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The Death Domain Kinase RIP Protects Thymocytes from Tumor Necrosis Factor Receptor Type 2–induced Cell Death

Fas and the tumor necrosis factor receptor (TNFR)1 regulate the programmed cell death of lymphocytes. The death domain kinase, receptor interacting protein (rip), is recruited to the TNFR1 upon receptor activation. In vitro, rip (−/−) fibroblasts are sensitive to TNF-induced cell death due to an imp...

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Detalhes bibliográficos
Main Authors: Cusson, Nicole, Oikemus, Sarah, Kilpatrick, Elizabeth D., Cunningham, Leslie, Kelliher, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194008/
https://ncbi.nlm.nih.gov/pubmed/12093867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011470
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