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Crosstalk Between BCR/ABL Oncoprotein and CXCR4 Signaling through a Src Family Kinase in Human Leukemia Cells

Stromal-derived factor (SDF)-1 and its G protein–coupled receptor, CXCR4, regulate stem/progenitor cell migration and retention in the marrow and are required for hematopoiesis. We show here an interaction between CXCR4 and the Src-related kinase, Lyn, in normal progenitors. We demonstrate that CXCR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ptasznik, Andrzej, Urbanowska, Elzbieta, Chinta, Suneetha, Costa, Melinda A., Katz, Benjamin A., Stanislaus, Marisha A., Demir, Gokhan, Linnekin, Diana, Pan, Zhixing K., Gewirtz, Alan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193994/
https://ncbi.nlm.nih.gov/pubmed/12208881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020519
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