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Uncoupling of Proliferative Potential and Gain of Effector Function by CD8(+) T Cells Responding to Self-Antigens
Professional antigen-presenting cells (APCs) are capable of transporting self-antigens from peripheral tissues to secondary lymphoid organs where they are presented to potentially autoreactive CD8(+) T cells. In the absence of an inflammatory response, this results in immune tolerance. The presence...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193940/ https://ncbi.nlm.nih.gov/pubmed/12163561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011612 |
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