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Pancreatic Lymph Nodes Are Required for Priming of β Cell Reactive T Cells in NOD Mice

Nonobese diabetic (NOD) mice develop spontaneous autoimmune diabetes that results from the destruction of insulin secreting β cells by diabetogenic T cells. The time and location of the encounter of autoantigen(s) by naive autoreactive T cells in normal NOD mice are still elusive. To address these i...

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Autors principals: Gagnerault, Marie-Claude, Luan, Jian Jian, Lotton, Chantal, Lepault, Françoise
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193939/
https://ncbi.nlm.nih.gov/pubmed/12163565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011353
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