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T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses
Nonobese diabetic (NOD) mice develop spontaneous autoimmune Type 1 diabetes (T1D) that results from the destruction of insulin secreting β cells by diabetogenic T cells. The activation of autoreactive T cells occurs in the pancreatic lymph nodes (PLN) from where effector T cells migrate to the pancr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774157/ https://ncbi.nlm.nih.gov/pubmed/22580347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.04.004 |
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