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Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes
CD8(+) class I–restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed. However, escape mutation depends on the net balance of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193781/ https://ncbi.nlm.nih.gov/pubmed/12743169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022138 |
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