Mechanisms of Arsenical and Diamidine Uptake and Resistance in Trypanosoma brucei

Sleeping sickness, caused by Trypanosoma brucei spp., has become resurgent in sub-Saharan Africa. Moreover, there is an alarming increase in treatment failures with melarsoprol, the principal agent used against late-stage sleeping sickness. In T. brucei, the uptake of melarsoprol as well as diamidin...

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Hauptverfasser: Matovu, Enock, Stewart, Mhairi L., Geiser, Federico, Brun, Reto, Mäser, Pascal, Wallace, Lynsey J. M., Burchmore, Richard J., Enyaru, John C. K., Barrett, Michael P., Kaminsky, Ronald, Seebeck, Thomas, de Koning, Harry P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC219364/
https://ncbi.nlm.nih.gov/pubmed/14555482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.5.1003-1008.2003
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