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Mechanisms of Arsenical and Diamidine Uptake and Resistance in Trypanosoma brucei

Sleeping sickness, caused by Trypanosoma brucei spp., has become resurgent in sub-Saharan Africa. Moreover, there is an alarming increase in treatment failures with melarsoprol, the principal agent used against late-stage sleeping sickness. In T. brucei, the uptake of melarsoprol as well as diamidin...

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主要な著者: Matovu, Enock, Stewart, Mhairi L., Geiser, Federico, Brun, Reto, Mäser, Pascal, Wallace, Lynsey J. M., Burchmore, Richard J., Enyaru, John C. K., Barrett, Michael P., Kaminsky, Ronald, Seebeck, Thomas, de Koning, Harry P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC219364/
https://ncbi.nlm.nih.gov/pubmed/14555482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.5.1003-1008.2003
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