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Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss

The antiphospholipid syndrome (APS) is characterized by recurrent fetal loss, vascular thrombosis, and thrombocytopenia occurring in the presence of antiphospholipid (aPL) antibodies. The pathogenesis of fetal loss and tissue injury in APS is incompletely understood, but is thought to involve platel...

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Autors principals: Holers, V. Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M., Molina, Hector, Pierangeli, Silvia S., Espinola, Ricardo, Xiaowei, Liu E., Mao, Dailing, Vialpando, Christopher G., Salmon, Jane E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193604/
https://ncbi.nlm.nih.gov/pubmed/11805148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.200116116
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