Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss

The antiphospholipid syndrome (APS) is characterized by recurrent fetal loss, vascular thrombosis, and thrombocytopenia occurring in the presence of antiphospholipid (aPL) antibodies. The pathogenesis of fetal loss and tissue injury in APS is incompletely understood, but is thought to involve platel...

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Bibliographic Details
Main Authors: Holers, V. Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M., Molina, Hector, Pierangeli, Silvia S., Espinola, Ricardo, Xiaowei, Liu E., Mao, Dailing, Vialpando, Christopher G., Salmon, Jane E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193604/
https://ncbi.nlm.nih.gov/pubmed/11805148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.200116116
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