Blocking Chemokine Responsive to γ–2/Interferon (IFN)-γ Inducible Protein and Monokine Induced by IFN-γ Activity In Vivo Reduces the Pathogenetic but not the Antiviral Potential of Hepatitis B Virus–specific Cytotoxic T Lymphocytes

Using transgenic mice that replicate hepatitis B virus (HBV) at high levels in the liver as recipients of HBV-specific cytotoxic T lymphocytes (CTLs), we showed that the chemokines responsive to γ–2/IFN-γ inducible protein ([Crg2]IP-10) and monokine induced by interferon-γ (Mig) are rapidly and stro...

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Detalhes bibliográficos
Main Authors: Kakimi, Kazuhiro, Lane, Thomas E., Wieland, Stefan, Asensio, Valerie C., Campbell, Iain L., Chisari, Francis V., Guidotti, Luca G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193580/
https://ncbi.nlm.nih.gov/pubmed/11748277
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