Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

B cell–derived chronic lymphocytic leukemia (B-CLL) represents a common malignancy whose cell derivation and pathogenesis are unknown. Recent studies have shown that >50% of CLLs display hypermutated immunoglobulin variable region (IgV) sequences and a more favorable prognosis, suggesting that th...

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Autori principali: Klein, Ulf, Tu, Yuhai, Stolovitzky, Gustavo A., Mattioli, Michela, Cattoretti, Giorgio, Husson, Hervé, Freedman, Arnold, Inghirami, Giorgio, Cro, Lilla, Baldini, Luca, Neri, Antonino, Califano, Andrea, Dalla-Favera, Riccardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193527/
https://ncbi.nlm.nih.gov/pubmed/11733577
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