Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation

Syncytia arising from the fusion of cells expressing a lymphotropic human immunodeficiency virus (HIV)-1–encoded envelope glycoprotein complex (Env) gene with cells expressing the CD4/CXCR4 complex undergo apoptosis through a mitochondrion-controlled pathway initiated by the upregulation of Bax. In...

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Detalhes bibliográficos
Main Authors: Castedo, Maria, Ferri, Karine F., Blanco, Julià, Roumier, Thomas, Larochette, Nathanael, Barretina, Jordi, Amendola, Alessandra, Nardacci, Roberta, Métivier, Didier, Este, José A., Piacentini, Mauro, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193513/
https://ncbi.nlm.nih.gov/pubmed/11602639
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