T Cell Development and T Cell Responses in Mice with Mutations Affecting Tyrosines 292 or 315 of the Zap-70 Protein Tyrosine Kinase

After stimulation of the T cell receptor (TCR), the tyrosine residues 292 and 315 in interdomain B of the protein tyrosine kinase ZAP-70 become phosphorylated and plausibly function as docking sites for Cbl and Vav1, respectively. The two latter proteins have been suggested to serve as substrates fo...

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Detalhes bibliográficos
Main Authors: Magnan, Antoine, Di Bartolo, Vincenzo, Mura, Anne-Marie, Boyer, Claude, Richelme, Mireille, Lin, Yea-Lih, Roure, Agnès, Gillet, Anne, Arrieumerlou, Cécile, Acuto, Oreste, Malissen, Bernard, Malissen, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193493/
https://ncbi.nlm.nih.gov/pubmed/11514605
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