Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine: Comparison of Prophylaxis and Therapy

We have previously shown that small B16 melanomas can be successfully treated using a combination of anti–cytotoxic T lymphocyte antigen (CTLA)-4 monoclonal antibody with a granulocyte/macrophage colony-stimulating factor (GM-CSF) producing irradiated tumor cell vaccine. Regression of tumors results...

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Detalhes bibliográficos
Main Authors: van Elsas, Andrea, Sutmuller, Roger P.M., Hurwitz, Arthur A., Ziskin, Jennifer, Villasenor, Jennifer, Medema, Jan-Paul, Overwijk, Willem W., Restifo, Nicholas P., Melief, Cornelis J.M., Offringa, Rienk, Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193490/
https://ncbi.nlm.nih.gov/pubmed/11514604
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