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A Naturally Processed Mitochondrial Self-Peptide in Complex with Thymic Mhc Molecules Functions as a Selecting Ligand for a Viral-Specific T Cell Receptor

Peptide fragments of self-proteins bound to major histocompatibility complex molecules within the thymus are important for positively selecting T cell receptor (TCR)-bearing CD4(+)CD8(+) double positive (DP) thymocytes for further maturation. The relationship between naturally processed thymic self-...

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Main Authors: Sasada, Tetsuro, Ghendler, Yoseph, Neveu, John M., Lane, William S., Reinherz, Ellis L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2001
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193488/
https://ncbi.nlm.nih.gov/pubmed/11581311
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