Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation

The receptor subunit gp130 transduces multiple cell type–specific activities of the leukemia inhibitory factor (LIF)/interleukin (IL)-6 family of cytokines through the signal transducer and activator of transcription (STAT) and src homology 2 domain–bearing protein tyrosine phosphatase (SHP)-2/ras/E...

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Autors principals: Ernst, Matthias, Inglese, Melissa, Waring, Paul, Campbell, Ian K., Bao, Shisan, Clay, Fiona J., Alexander, Warren S., Wicks, Ian P., Tarlinton, David M., Novak, Ulrike, Heath, Joan K., Dunn, Ashley R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193459/
https://ncbi.nlm.nih.gov/pubmed/11457894
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