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Constitutively Activated Akt-1 Is Vital for the Survival of Human Monocyte-Differentiated Macrophages: Role of Mcl-1, Independent of Nuclear Factor (Nf)-κb, Bad, or Caspase Activation
Recent data from mice deficient for phosphatase and tensin homologue deleted from chromosome 10 or src homology 2 domain–containing 5′ inositol phosphatase, phosphatases that negatively regulate the phosphatidylinositol 3-kinase (PI3K) pathway, revealed an increased number of macrophages in these an...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193455/ https://ncbi.nlm.nih.gov/pubmed/11457886 |
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