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Macrophages Require Constitutive NF-κB Activation To Maintain A1 Expression and Mitochondrial Homeostasis

NF-κB is a critical mediator of macrophage inflammatory responses, but its role in regulating macrophage survival has yet to be elucidated. Here, we demonstrate that constitutive NF-κB activation is essential for macrophage survival. Blocking the constitutive activation of NF-κB with pyrrolidine dit...

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Detalhes bibliográficos
Main Authors: Pagliari, Lisa J., Perlman, Harris, Liu, Hongtao, Pope, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116114/
https://ncbi.nlm.nih.gov/pubmed/11073986
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