Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies

The peroxisome proliferator–activated receptor γ (PPARγ) is highly expressed in the colon mucosa and its activation has been reported to protect against colitis. We studied the involvement of PPARγ and its heterodimeric partner, the retinoid X receptor (RXR) in intestinal inflammatory responses. PPA...

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Autors principals: Desreumaux, Pierre, Dubuquoy, Laurent, Nutten, Sophie, Peuchmaur, Michel, Englaro, Walter, Schoonjans, Kristina, Derijard, Benoit, Desvergne, Beatrice, Wahli, Walter, Chambon, Pierre, Leibowitz, Mark D., Colombel, Jean-Frédéric, Auwerx, Johan
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193371/
https://ncbi.nlm.nih.gov/pubmed/11283155
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