Signal Transducer and Activator of Transcription (Stat)-Induced Stat Inhibitor 1 (Ssi-1)/Suppressor of Cytokine Signaling 1 (Socs1) Inhibits Insulin Signal Transduction Pathway through Modulating Insulin Receptor Substrate 1 (Irs-1) Phosphorylation

Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1) is known to function as a negative feedback regulator of cytokine signaling, but it is unclear whether it is involved in other biological events. Here, we show that SSI-1 participates and plays an important role...

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Autors principals: Kawazoe, Yoshinori, Naka, Tetsuji, Fujimoto, Minoru, Kohzaki, Hidetsugu, Morita, Yoshiaki, Narazaki, Masashi, Okumura, Kohichi, Saitoh, Hiroshi, Nakagawa, Reiko, Uchiyama, Yasuo, Akira, Shizuo, Kishimoto, Tadamitsu
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193341/
https://ncbi.nlm.nih.gov/pubmed/11208867
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