Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

Cytokine-inducible protein SSI-1 [signal transducers and activators of transcription (STAT)-induced STAT inhibitor 1, also referred to as SOCS-1 (suppressor of cytokine signaling 1) or JAB (Janus kinase-binding protein)] negatively regulates cytokine receptor signaling by inhibition of JAK kinases....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Narazaki, Masashi, Fujimoto, Minoru, Matsumoto, Tomoshige, Morita, Yoshiaki, Saito, Hiroshi, Kajita, Tadahiro, Yoshizaki, Kazuyuki, Naka, Tetsuji, Kishimoto, Tadamitsu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13130
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