Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

Cytokine-inducible protein SSI-1 [signal transducers and activators of transcription (STAT)-induced STAT inhibitor 1, also referred to as SOCS-1 (suppressor of cytokine signaling 1) or JAB (Janus kinase-binding protein)] negatively regulates cytokine receptor signaling by inhibition of JAK kinases....

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Detalhes bibliográficos
Main Authors: Narazaki, Masashi, Fujimoto, Minoru, Matsumoto, Tomoshige, Morita, Yoshiaki, Saito, Hiroshi, Kajita, Tadahiro, Yoshizaki, Kazuyuki, Naka, Tetsuji, Kishimoto, Tadamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23734/
https://ncbi.nlm.nih.gov/pubmed/9789053
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