Akt-Dependent Cytokine Production in Mast Cells

Cross-linking of FcεRI induces the activation of three protein tyrosine kinases, Lyn, Syk, and Bruton's tyrosine kinase (Btk), leading to the secretion of a panel of proinflammatory mediators from mast cells. This study showed phosphorylation at Ser-473 and enzymatic activation of Akt/protein k...

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Autores principales: Kitaura, Jiro, Asai, Koichi, Maeda-Yamamoto, Mari, Kawakami, Yuko, Kikkawa, Ushio, Kawakami, Toshiaki
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193272/
https://ncbi.nlm.nih.gov/pubmed/10974038
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