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B-1 and B-2 Cell–Derived Immunoglobulin M Antibodies Are Nonredundant Components of the Protective Response to Influenza Virus Infection

We have studied the role of secreted immunoglobulin (Ig)M in protection from infection with influenza virus and delineated the relative contributions of B-1 versus B-2 cell–derived IgM in this process. Mice deficient in secreted IgM but capable of expressing surface IgM and secreting other Ig classe...

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Detalhes bibliográficos
Main Authors: Baumgarth, Nicole, Herman, Ometa C., Jager, Gina C., Brown, Lorena E., Herzenberg, Leonore A., Chen, Jianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193249/
https://ncbi.nlm.nih.gov/pubmed/10899913
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