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Identification of a germ-line pro-B cell subset that distinguishes the fetal/neonatal from the adult B cell development pathway

Studies presented here show that the expression of CD4, MHC class II (Ia,) and B220 cleanly resolves a major and a minor subset within the earliest pro-B cell population (germ-line pro-B) in adult bone marrow (BM). The major subset expresses intermediate B220 and low CD4 levels. The minor subset, wh...

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Autors principals: Lu, Li-Sheng, Tung, James, Baumgarth, Nicole, Herman, Ometa, Gleimer, Michael, Herzenberg, Leonard A., Herzenberg, Leonore A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122463/
https://ncbi.nlm.nih.gov/pubmed/11867763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052715399
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